Simple Roasted Butternut Squash Ingredients 1 butternut squash - peeled, seeded, and cut into 1-inch cubes 2 tablespoons olive oil 2 cloves garlic, minced 1 pinch salt and ground black pepper to taste Method Preheat oven to 400 degrees F (200 degrees C). Toss butternut squash with olive oil and garlic in a large bowl. Season with salt and black pepper. Arrange coated squash on a baking sheet. Roast in the preheated oven until squash is tender and lightly browned, 25 to 30 minutes.